Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis.

 

  • Essentials Coagulation Factor (F) XI is a safe target for the development of antithrombotics. We designed an antigen comprising the human FXI catalytic domain and diphtheria toxin T domain. Antigen immunization reduced plasma FXI activity by 54% and prevented thrombosis in mice. FXI vaccination can serve as an effective strategy for thrombosis prevention.

 

  • Background Coagulation factor XI serves as a signal amplifier in the intrinsic coagulation pathway. Blockade of FXI by mAbs or small-molecule inhibitors inhibits thrombosis without causing severe bleeding, which is an inherent risk of currently available antithrombotic agents.

          Coagulation Factor XII (F12) Antibody (Biotin)

  • Objectives To design an FXI vaccine and assess its efficacy in inhibiting FXI activity and preventing thrombosis. Methods An FXI antigen was generated by fusing the catalytic domain of human FXI to the C-terminus of the transmembrane domain of diphtheria toxin.

 

  • The anti-FXI antibody response, plasma FXI activity and antithrombotic efficacy in mice immunized with the FXI antigen were examined. Results The antigen elicited a significant antibody response against mouse FXI, and reduced the plasma FXI activity by 54.0% in mice. FXI vaccination markedly reduced the levels of coagulation and inflammation in a mouse model of inferior vena cava stenosis.

       Mouse Coagulation Factor XII (F12) ELISA Kit

  • Significant protective effects were also observed in mouse models of venous thrombosis and pulmonary embolism. Conclusions Our data demonstrate that FXI vaccination can serve as an effective strategy for thrombosis prevention.

Eukaryotic Coagulation Factor XII (F12)
4-EPA677Mu61
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Uniprot ID: Q80YC5
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 65.3kDa
  • Isoelectric Point: 6.9

Coagulation Factor XII (F12) Antibody
20-abx111707
  • EUR 732.00
  • EUR 398.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx001419
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx102116
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XII (F12) Antibody
20-abx102117
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XII (F12) Antibody
abx034465-400ul 400 ul
EUR 523.00
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
abx034465-80l 80 µl
EUR 286.00
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
abx030904-400ul 400 ul
EUR 523.00
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
abx030904-80l 80 µl
EUR 286.00
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx175919
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-12 working days.

Coagulation Factor XII (F12) Antibody
20-abx323704
  • EUR 314.00
  • EUR 244.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx324566
  • EUR 314.00
  • EUR 244.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx333983
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx319476
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody
20-abx171818
  • EUR 787.00
  • EUR 411.00
  • 0
  • 1
  • Please enquire.

Pig Coagulation factor XII (F12)
1-CSB-YP007918PI
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • MW: 41.8 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.

Pig Coagulation factor XII (F12)
1-CSB-EP007918PI
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • MW: 43.8 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.

Recombinant Coagulation Factor XII (F12)
4-RPA677Hu01
  • EUR 512.16
  • EUR 240.00
  • EUR 1645.60
  • EUR 615.20
  • EUR 1130.40
  • EUR 406.00
  • EUR 3964.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Uniprot ID: P00748
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 27.2kDa
  • Isoelectric Point: 5.5

Recombinant Coagulation Factor XII (F12)
4-RPA677Mu01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Uniprot ID: Q80YC5
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 29.1kDa
  • Isoelectric Point: 5.7

Human Coagulation Factor XII ELISA kit
E01F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Human Coagulation Factor XII ELISA kit
E01F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Human Coagulation Factor XII ELISA kit
E01F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Human coagulation factor XII ELISA Kit
ELA-E0677h 96 Tests
EUR 824.00

Human Coagulation Factor XII (F12) Protein
20-abx065987
  • EUR 718.00
  • EUR 286.00
  • EUR 2221.00
  • EUR 857.00
  • EUR 509.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Goat Coagulation Factor XII ELISA kit
E06F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Goat Coagulation Factor XII ELISA kit
E06F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Goat Coagulation Factor XII ELISA kit
E06F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rat Coagulation Factor XII ELISA kit
E02F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rat Coagulation Factor XII ELISA kit
E02F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rat Coagulation Factor XII ELISA kit
E02F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XII ELISA kit
E03F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XII ELISA kit
E03F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XII ELISA kit
E03F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rabbit Coagulation Factor XII ELISA kit
E04F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rabbit Coagulation Factor XII ELISA kit
E04F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rabbit Coagulation Factor XII ELISA kit
E04F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Dog Coagulation Factor XII ELISA kit
E08F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Dog Coagulation Factor XII ELISA kit
E08F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Dog Coagulation Factor XII ELISA kit
E08F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Monkey Coagulation Factor XII ELISA kit
E09F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Monkey Coagulation Factor XII ELISA kit
E09F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Monkey Coagulation Factor XII ELISA kit
E09F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Pig Coagulation Factor XII ELISA kit
E07F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Pig Coagulation Factor XII ELISA kit
E07F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Pig Coagulation Factor XII ELISA kit
E07F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XII (F12) Protein
20-abx065988
  • EUR 676.00
  • EUR 286.00
  • EUR 2082.00
  • EUR 801.00
  • EUR 481.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XII (F12) Antibody (HRP)
20-abx335142
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody (FITC)
20-abx335143
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody (Biotin)
20-abx335144
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody (HRP)
20-abx319477
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody (FITC)
20-abx319478
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Coagulation Factor XII (F12) Antibody (Biotin)
20-abx319479
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Human Coagulation Factor XII (F12) ELISA Kit
abx570144-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

ELISA kit for Human Coagulation factor XII
EK2136 96 tests
EUR 553.00

Human F12/ Coagulation factor XII ELISA Kit
E0833Hu 1 Kit
EUR 571.00

Human F12(Coagulation factor XII) ELISA Kit
EH1012 96T
EUR 476.25
  • Detection range: 3.125-200 ng/ml
  • Uniprot ID: P00748
  • Alias: F12(Coagulation factor XII)/HAEX/Hageman factor/HAE3/HAF

Human Coagulation factor XII, F12 ELISA KIT
ELI-02420h 96 Tests
EUR 824.00

Human Coagulation Factor XII (F12) ELISA Kit
20-abx151465
  • EUR 6642.00
  • EUR 3542.00
  • EUR 825.00
  • 0
  • 1
  • 2
  • Shipped within 5-7 working days.

Human Coagulation Factor XII (F12) CLIA Kit
abx196535-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Human Coagulation Factor XII (F12) CLIA Kit
20-abx491868
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 0
  • 1
  • 2
  • Please enquire.

Human Coagulation Factor XII (F12) ELISA Kit
abx250251-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Human Coagulation Factor XII (F12) ELISA Kit
DLR-F12-Hu-48T 48T
EUR 479.00
  • Should the Human Coagulation Factor XII (F12) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.

Human Coagulation Factor XII (F12) ELISA Kit
DLR-F12-Hu-96T 96T
EUR 621.00
  • Should the Human Coagulation Factor XII (F12) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.

Human Coagulation factor XII(F12) ELISA kit
CSB-EL007918HU-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.

Human Coagulation factor XII(F12) ELISA kit
1-CSB-EL007918HU
  • EUR 703.00
  • EUR 4843.00
  • EUR 2570.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.

Coagulation Factor XII (F12) Polyclonal Antibody (Human)
4-PAA677Hu01
  • EUR 232.00
  • EUR 2285.00
  • EUR 574.00
  • EUR 289.00
  • EUR 208.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Sequence of the immunogen: F12 (Ser400~Ser615)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Human Coagulation Factor XII (F12) ELISA Kit
SEA677Hu-10x96wellstestplate 10x96-wells test plate
EUR 4273.35
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XII (F12) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XII (F12) ELISA Kit
SEA677Hu-1x48wellstestplate 1x48-wells test plate
EUR 439.57
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XII (F12) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XII (F12) ELISA Kit
SEA677Hu-1x96wellstestplate 1x96-wells test plate
EUR 585.10
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XII (F12) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XII (F12) ELISA Kit
SEA677Hu-5x96wellstestplate 5x96-wells test plate
EUR 2332.95
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XII (F12) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XII (F12) ELISA Kit
4-SEA677Hu
  • EUR 4324.00
  • EUR 2283.00
  • EUR 586.00
  • 0
  • 1
  • 2
  • Known also as Coagulation Factor XII elisa. Alternative names of the recognized antigen: FXII
  • HAF
  • Contact Factor
  • Hageman Factor

Human Coagulation Factor XII (F12) ELISA Kit
RD-F12-Hu-48Tests 48 Tests
EUR 478.00

Human Coagulation Factor XII (F12) ELISA Kit
RD-F12-Hu-96Tests 96 Tests
EUR 662.00

Human Coagulation Factor XII (F12) ELISA Kit
RDR-F12-Hu-48Tests 48 Tests
EUR 500.00

Human Coagulation Factor XII (F12) ELISA Kit
RDR-F12-Hu-96Tests 96 Tests
EUR 692.00

anti- Factor XII antibody
FNab02938 100µg
EUR 505.25
  • Immunogen: coagulation factor XII(Hageman factor)
  • Uniprot ID: P00748
  • Research Area: Cardiovascular, Metabolism

anti- Factor XII antibody
FNab02939 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:50-1:500
  • IF: 1:50-1:500
  • Immunogen: coagulation factor XII(Hageman factor)
  • Uniprot ID: P00748
  • Research Area: Cardiovascular, Metabolism

Anti-Factor XII antibody
PAab02938 100 ug
EUR 355.00

Anti-Factor XII (3A3)
YF-MA12927 100 ug
EUR 363.00

Rabbit Coagulation Factor XII (F12) ELISA Kit
abx362129-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Cow Coagulation Factor XII (F12) ELISA Kit
abx513739-96tests 96 tests
EUR 911.00
  • Shipped within 5-12 working days.

Rat Coagulation Factor XII (F12) ELISA Kit
abx513743-96tests 96 tests
EUR 707.00
  • Shipped within 5-12 working days.

Mouse Coagulation Factor XII (F12) ELISA Kit
abx573343-96tests 96 tests
EUR 707.00
  • Shipped within 5-12 working days.

Guinea pig Coagulation Factor XII ELISA kit
E05F0027-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Guinea pig Coagulation Factor XII ELISA kit
E05F0027-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Guinea pig Coagulation Factor XII ELISA kit
E05F0027-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation factor XII, F12 ELISA KIT
ELI-02416m 96 Tests
EUR 865.00

Bovine Coagulation factor XII, F12 ELISA KIT
ELI-02417b 96 Tests
EUR 928.00

Porcine Coagulation factor XII, F12 ELISA KIT
ELI-02418p 96 Tests
EUR 928.00

Mouse FXII(Coagulation Factor XII) ELISA Kit
EM1046 96T
EUR 524.10
  • Detection range: 3.125-200 ng/ml
  • Alias: FXII/F12/F12(Coagulation factor XII)/HAEX/Hageman factor/HAE3/HAF

Excess of heme induces tissue factor-dependent activation of coagulation in mice.

 

  • An excess of free heme is present in the blood during many types of hemolytic anemia. This has been linked to organ damage caused by heme-mediated oxidative stress and vascular inflammation. We investigated the mechanism of heme-induced coagulation activation in vivo.

 

  • Heme caused coagulation activation in wild-type mice that was attenuated by an anti-tissue factor antibody and in mice expressing low levels of tissue factor. In contrast, neither factor XI deletion nor inhibition of factor XIIa-mediated factor XI activation reduced heme-induced coagulation activation, suggesting that the intrinsic coagulation pathway is not involved. We investigated the source of tissue factor in heme-induced coagulation activation.

       Rat Coagulation Factor XI (F11) Protein | Coagulation Factor XI (F11) Antibody (HRP)

  • Heme increased the procoagulant activity of mouse macrophages and human PBMCs. Tissue factor-positive staining was observed on leukocytes isolated from the blood of heme-treated mice but not on endothelial cells in the lungs. Furthermore, heme increased vascular permeability in the mouse lungs, kidney and heart.

 

  • Deletion of tissue factor from either myeloid cells, hematopoietic or endothelial cells, or inhibition of tissue factor expressed by non-hematopoietic cells did not reduce heme-induced coagulation activation. However, heme-induced activation of coagulation was abolished when both non-hematopoietic and hematopoietic cell tissue factor was inhibited.

Human Coagulation factor XI (F11)
1-CSB-EP007916HU
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • MW: 45.2 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.

Mouse Coagulation Factor XI ELISA kit
E03F0026-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XI ELISA kit
E03F0026-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XI ELISA kit
E03F0026-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Mouse Coagulation Factor XI (F11) Protein
20-abx065986
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XI (F11) Antibody
20-abx215271
  • EUR 425.00
  • EUR 342.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Coagulation Factor XI (F11) Antibody
20-abx101988
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XI (F11) Antibody
20-abx101989
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XI (F11) Antibody
20-abx130293
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Coagulation Factor XI (F11) Antibody
abx122726-100ug 100 ug
EUR 391.00
  • Shipped within 5-10 working days.

Coagulation Factor XI (F11) Antibody
20-abx171816
  • EUR 815.00
  • EUR 425.00
  • 0
  • 1
  • Please enquire.

Coagulation Factor XI (F11) Antibody
20-abx171817
  • EUR 871.00
  • EUR 453.00
  • 0
  • 1
  • Please enquire.

Coagulation Factor XI (F11) Antibody
20-abx301182
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-10 working days.

Recombinant Coagulation Factor XI (F11)
4-RPB834Hu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Uniprot ID: P03951
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 28.9kDa
  • Isoelectric Point: 9.1

Recombinant Coagulation Factor XI (F11)
4-RPB834Mu01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Uniprot ID: Inquire
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 29.9kDa
  • Isoelectric Point: 9.3

Recombinant Coagulation Factor XI (F11)
4-RPB834Ra01
  • EUR 548.00
  • EUR 250.00
  • EUR 1780.00
  • EUR 660.00
  • EUR 1220.00
  • EUR 430.00
  • EUR 4300.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Uniprot ID: Q6TUF8
  • Buffer composition: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 57.2kDa
  • Isoelectric Point: 6.5

Human Coagulation Factor XI ELISA kit
E01F0026-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Human Coagulation Factor XI ELISA kit
E01F0026-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Human Coagulation Factor XI ELISA kit
E01F0026-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Human Coagulation Factor XI (F11) Protein
20-abx065983
  • EUR 690.00
  • EUR 286.00
  • EUR 2124.00
  • EUR 815.00
  • EUR 495.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Shipped within 5-7 working days.

Mouse F11/ Coagulation factor XI ELISA Kit
E0481Mo 1 Kit
EUR 571.00

Mouse Coagulation Factor XI (F11) ELISA Kit
abx254821-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

ELISA kit for Mouse Coagulation factor XI
EK2353 96 tests
EUR 553.00

Mouse Coagulation factor XI, F11 ELISA KIT
ELI-02897m 96 Tests
EUR 865.00

Mouse F11(Coagulation factor XI) ELISA Kit
EM0468 96T
EUR 567.60
  • Detection range: 3.125-200 ng/ml
  • Uniprot ID: Q91Y47
  • Alias: F11/Coagulation factor XI/FXI/Plasma thromboplastin antecedent/PTA

Coagulation Factor XI (F11) Polyclonal Antibody (Mouse)
4-PAB834Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Sequence of the immunogen: Pro157~Arg389
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Mouse Coagulation Factor XI(F11)ELISA kit
QY-E20354 96T
EUR 361.00

Human Coagulation Factor XI (F11) ELISA Kit
DLR-F11-Hu-48T 48T
EUR 498.00
  • Should the Human Coagulation Factor XI (F11) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.

Human Coagulation Factor XI (F11) ELISA Kit
DLR-F11-Hu-96T 96T
EUR 647.00
  • Should the Human Coagulation Factor XI (F11) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.

Human Coagulation Factor XI (F11) CLIA Kit
abx196534-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Human Coagulation Factor XI (F11) ELISA Kit
20-abx151110
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 0
  • 1
  • 2
  • Shipped within 5-7 working days.

Human Coagulation Factor XI (F11) ELISA Kit
abx250314-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

ELISA kit for Human Coagulation factor XI
EK2354 96 tests
EUR 553.00

Human F11/ Coagulation factor XI ELISA Kit
E0832Hu 1 Kit
EUR 571.00

Human F11(Coagulation factor XI) ELISA Kit
EH1071 96T
EUR 476.25
  • Detection range: 0.313-20 ng/ml
  • Uniprot ID: P03951
  • Alias: F11(Coagulation Factor XI)/FXI/FXIPlasma thromboplastin antecedent/PTA

Human Coagulation factor XI, F11 ELISA KIT
ELI-02895h 96 Tests
EUR 824.00

Human Coagulation factor XI(F11) ELISA kit
CSB-EL007916HU-24T 1 plate of 24 wells
EUR 165.00
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.

Human Coagulation factor XI(F11) ELISA kit
1-CSB-EL007916HU
  • EUR 804.00
  • EUR 5099.00
  • EUR 2704.00
  • 0
  • 1
  • 2
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.

Human Coagulation Factor XI (F11) ELISA Kit
abx572158-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Human Coagulation Factor XI (F11) CLIA Kit
20-abx493138
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 0
  • 1
  • 2
  • Please enquire.

Coagulation Factor XI (F11) Polyclonal Antibody (Human)
4-PAB834Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
  • 0
  • 1
  • 2
  • 3
  • 4
  • Sequence of the immunogen: F11 (Thr170~Glu398)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Human Coagulation Factor XI(F11)ELISA Kit
QY-E02020 96T
EUR 361.00

Human Coagulation Factor XI ELISA Kit (F11)
RK01336 96 Tests
EUR 521.00

Human Coagulation Factor XI (F11) ELISA Kit
RDR-F11-Hu-48Tests 48 Tests
EUR 522.00

Human Coagulation Factor XI (F11) ELISA Kit
RDR-F11-Hu-96Tests 96 Tests
EUR 724.00

Human Coagulation Factor XI (F11) ELISA Kit
SEB834Hu-10x96wellstestplate 10x96-wells test plate
EUR 4502.43
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XI (F11) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XI (F11) ELISA Kit
SEB834Hu-1x48wellstestplate 1x48-wells test plate
EUR 458.44
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XI (F11) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XI (F11) ELISA Kit
SEB834Hu-1x96wellstestplate 1x96-wells test plate
EUR 612.05
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XI (F11) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XI (F11) ELISA Kit
SEB834Hu-5x96wellstestplate 5x96-wells test plate
EUR 2454.23
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Coagulation Factor XI (F11) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%

Human Coagulation Factor XI (F11) ELISA Kit
4-SEB834Hu
  • EUR 4553.00
  • EUR 2405.00
  • EUR 613.00
  • 0
  • 1
  • 2
  • Known also as Coagulation Factor XI elisa. Alternative names of the recognized antigen: FXI
  • PTA
  • Fletcher Factor
  • Prekallikrein
  • Plasma Thromboplastin Antecedent

Human Coagulation Factor XI (F11) ELISA Kit
RD-F11-Hu-48Tests 48 Tests
EUR 500.00

Human Coagulation Factor XI (F11) ELISA Kit
RD-F11-Hu-96Tests 96 Tests
EUR 692.00

Rat Coagulation Factor XI ELISA kit
E02F0026-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rat Coagulation Factor XI ELISA kit
E02F0026-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rat Coagulation Factor XI ELISA kit
E02F0026-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Goat Coagulation Factor XI ELISA kit
E06F0026-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Goat Coagulation Factor XI ELISA kit
E06F0026-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Goat Coagulation Factor XI ELISA kit
E06F0026-96 1 plate of 96 wells
EUR 685.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rabbit Coagulation Factor XI ELISA kit
E04F0026-192T 192 tests
EUR 1270.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more

Rabbit Coagulation Factor XI ELISA kit
E04F0026-48 1 plate of 48 wells
EUR 520.00
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
  • Finally, we demonstrated that coagulation activation was partially attenuated in sickle cell mice treated with recombinant hemopexin to neutralize free heme. Our results indicate that heme promotes tissue factor-dependent coagulation activation and induces tissue factor expression on leukocytes in vivo. We also demonstrated that free heme may contribute to thrombin generation in a mouse model of sickle cell disease.

 

  • We demonstrate that transduction of adipocytes with a simian immunodeficiency virus agm TYO1 (SIVagm)-based lentiviral vector carrying the human coagulation factor VIII gene (SIVhFVIII) resulted in expression of the human FVIII transgene in vitro and in db/db mice in vivo. Cultured human adipocytes were transduced with the SIVagm vector carrying the GFP gene in a dose-dependent manner and transduction of adipocytes with SIVhFVIII resulted in efficient expression of human coagulation factor VIII (hFVIII; 320 +/- 39.8 ng/10(6) adipocytes/24 h) in vitro. Based upon success