Effect Of Phosphoprotein phosphatase

Phosphoprotein phosphatase

  • Phosphoprotein phosphatase (protein phosphatase 1, protein phosphatase 2A, protein phosphatase 2B, protein phosphatase 2C, D protein phosphatase fosfospektrinska phosphatase, casein phosphatase, Aspergillus awamori acid.

 

  • Protein phosphatase, calcineurin, phosphatase 2A, phosphatase 2B phosphatase II, IB phosphatase, phosphatase C-II, polikatjonom modulated (PCM) phosphatase, fosfopiruvat dehydrogenase phosphatase, phosphatase SP dehydrogenase phosphatase alpha-keto acids of branched chain BCKDH phosphatase, 3-hydroxy 3-methylglutaryl.

        Recombinant Candida Albicans YPI1 Protein (aa 1-124)

  • Coenzyme reductase phosphatase , HMG-KoA reductase phosphatase, phosphatase H-II, III phosphatase, and phosphatase, protein phosphatase, phosphatase IV) is an enzyme with the systematic title phosphoprotein phosphohydrolase.

Yarrowia lipolytica YeastStrain: Po1g

FYY202-1SB 1 vial Ask for price

Recombinant Candida Albicans YPI1 Protein (aa 1-124)

VAng-Lsx06074-1mgEcoli 1 mg (E. coli)
EUR 2993

Recombinant Candida Albicans YPI1 Protein (aa 1-124)

VAng-Lsx06074-500gEcoli 500 µg (E. coli)
EUR 2140

Recombinant Candida Albicans YPI1 Protein (aa 1-124)

VAng-Lsx06074-50gEcoli 50 µg (E. coli)
EUR 1480

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

VAng-Lsx8856-1mgEcoli 1 mg (E. coli)
EUR 4555

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

VAng-Lsx8856-500gEcoli 500 µg (E. coli)
EUR 3080

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

VAng-Lsx8856-50gEcoli 50 µg (E. coli)
EUR 2098

Recombinant Staphylococcus Aureus Uncharacterized HTH-type transcriptional regulator Protein (aa 1-745)

VAng-Cr6487-inquire inquire Ask for price

Recombinant Human Regulator of Calcineurin 1

7-06082 5µg Ask for price

Recombinant Human Regulator of Calcineurin 1

7-06083 20µg Ask for price

Recombinant Human Regulator of Calcineurin 1

7-06084 1mg Ask for price

CLEC1B Human, C-type Lectin Domain Family 1, Member B, Human Recombinant Protein, Sf9

PROTQ9P126-1 Regular: 5ug
EUR 317

CKMT3 Creatine Kinase Muscle Type-3 Human Recombinant Protein

PROTP06732-1 Regular: 50ug
EUR 317

Recombinant Human Down-Regulator of Transcription 1

7-04996 5µg Ask for price

Recombinant Human Down-Regulator of Transcription 1

7-04997 25µg Ask for price

Recombinant Human Down-Regulator of Transcription 1

7-04998 1mg Ask for price

Recombinant human Phosphatase and actin regulator 1 

P2674 100ug Ask for price
  • Uniprot ID: Q9C0D0
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)

Recombinant human SLC2A4 regulator

P2685 100ug Ask for price
  • Uniprot ID: Q9NR83
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)

C-type natriuretic peptide (1-22) (human, rat, swine)

B5441-1 1 mg
EUR 276

TNNT2 Troponin T Type 2, Cardiac Isoform 3 Human Recombinant Protein

PROTP45379-1 Regular: 20ug
EUR 317

TNNI2 Human, Troponin I Type 2 Human Recombinant Protein, His Tag

PROTP48788-1 Regular: 10ug
EUR 317

Recombinant human Calcium-activated chloride channel regulator 1

P2354 100ug Ask for price
  • Uniprot ID: A8K7I4
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)

Recombinant Regulator Of G Protein Signaling 1 (RGS1)

4-RPD701Hu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q08116
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 53.9kDa
  • Isoelectric Point: Inquire

RCAN1 Regulator of Calcineurin 1 Human Recombinant Protein

PROTP53805 Regular: 20ug
EUR 317

type II collagen fragment

A1096-1 1 mg
EUR 108

IGF-1, human recombinant

P1016-.1 100 µg
EUR 763

Recombinant E.Coli Ferric Uptake Regulator

7-05221 5µg Ask for price

Recombinant E.Coli Ferric Uptake Regulator

7-05222 25µg Ask for price

Recombinant E.Coli Ferric Uptake Regulator

7-05223 1mg Ask for price

Nudix Type Motif 1 (Recombinant)

20-abx073162
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.

SPINT2 Human, Serine Peptidase Inhibitor, Kunitz Type 2 Human Recombinant Protein, Sf9

PROTO43291-1 Regular: 10ug
EUR 317

FNDC5 Human, Fibronectin Type III Domain Containing 5 Human Recombinant Protein, Yeast

PROTQ8NAU1-1 Regular: 10ug
EUR 317

SCN3B Human, Sodium Channel Voltage-Gated, Type III Beta Human Recombinant Protein, Sf9

PROTQ9NY72-1 Regular: 10ug
EUR 317

TNFR2 Human, Tumor Necrosis Factor Receptor Type 2 Human Recombinant Protein, His Tag

PROTP20333-1 Regular: 20ug
EUR 317

Haptoglobin, Human Plasma (Mixed Type)

7535-1
EUR 158

IL-1 beta, rat recombinant

P1019-1 1 mg
EUR 7288

ApoA-1, human recombinant protein

P1052-.1 100 µg
EUR 313

ApoA-1, human recombinant protein

P1052-1 1 mg
EUR 1553

WNT-1, human recombinant protein

P1068-1 1 mg
EUR 6940

Recombinant Human Gremlin-1 Protein

PROTO60565-1 50ug
EUR 317

Recombinant Human Galectin-1 Protein

PROTP09382-1 50ug
EUR 317

Recombinant Human PECAM-1 Protein

PROTP16284-1 50ug
EUR 317

Canine IGF-1 Recombinant Protein

R00148-1 5ug/vial
EUR 259

Recombinant Human ANG-1 Protein

PROTQ15389-1 20ug
EUR 317

Recombinant Murine Cardiotrophin-1 Protein

PROTQ60753-1 10ug
EUR 317

Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein

P1054-1 1 mg
EUR 3947

IL-1-beta Interleukin-1 betaHuman Recombinant Protein

PROTP01584-1 Regular: 10ug
EUR 317

MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein

PROTP03956-1 Regular: 20ug
EUR 317

Recombinant human WW domain-containing transcription regulator protein 1

P1854 100ug Ask for price
  • Uniprot ID: Q9GZV5
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)

Recombinant mouse Isoform 3 of Transcription elongation regulator 1

P2600 100ug Ask for price
  • Uniprot ID: Q8CGF7-3
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)

Recombinant Down Regulator Of Transcription 1, TBP Binding (DR1)

4-RPB259Hu01
  • EUR 485.28
  • EUR 233.00
  • EUR 1544.80
  • EUR 581.60
  • EUR 1063.20
  • EUR 388.00
  • EUR 3712.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q01658
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 22.2kDa
  • Isoelectric Point: 6.1

DR1 Down-Regulator of Transcription 1 Human Recombinant Protein

PROTQ01658 Regular: 25ug
EUR 317

CNPY1 Canopy FGF Signaling Regulator 1 Human Recombinant Protein

PROTQ3B7I2 Regular: 10ug
EUR 317

Recombinant human Vomeronasal type-1 receptor 1

P2426 100ug Ask for price
  • Uniprot ID: Q9GZP7
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator); Clone SPM176 (Concentrate)

RA0499-C.1 0.1 ml
EUR 125

NFAT Transcription Factor Regulator-1

HY-112778 100mg
EUR 3206

Pleiotropic Regulator 1 (PLRG1) Antibody

20-abx135866
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Pleiotropic Regulator 1 (PLRG1) Antibody

abx036574-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Pleiotropic Regulator 1 (PLRG1) Antibody

abx029065-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Pleiotropic Regulator 1 (PLRG1) Antibody

abx029065-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Regulator of Calcineurin 1 Protein

20-abx261975
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.

Pleiotropic Regulator 1 (PLRG1) Antibody

abx432047-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Pleiotropic Regulator 1 (PLRG1) Antibody

abx236556-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Reticulophagy Regulator 1 (FAM134B) Antibody

20-abx301817
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein

PROTO75771-1 Regular: 10ug
EUR 317

JE (MCP-1), murine recombinant protein

P1034-1 1 mg
EUR 3878

IFN-alpha 1, human recombinant protein

P1058-.1 100 µg
EUR 313

IFN-alpha 1, human recombinant protein

P1058-1 1 mg
EUR 2277

OryzaExp? IGF-1 LR3, Human Recombinant

P1399-1
EUR 881

Phosphatase

phosphatase is an enzyme that removes a phosphate group from its substrate by hydrolysing phosphoric acid monoesters right into a phosphate ion and a molecule with a free hydroxyl group (see dephosphorylation). This motion is instantly reverse to that of phosphorylases and kinases, which connect phosphate teams to their substrates by utilizing energetic molecules like ATP. A standard phosphatase in lots of organisms is alkaline phosphatase.

 

Protein phosphorylation is the most typical and necessary type of reversible protein posttranslational modification (PTM), with as much as 30% of all proteins being phosphorylated at any given time. Protein kinases (PKs) are the impactors of phosphorylation and catalyse the switch of a γ-phosphate from ATP to particular amino acids on proteins.

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

A number of hundred PKs exist in mammals and are labeled into distinct super-families. Proteins are phosphorylated predominantly on Ser, Thr and Tyr residues, which account for 86, 12 and a pair of% respectively of the phosphoproteome, at the very least in mammals. In distinction, protein phosphatases (PPs) are the first effectors of dephosphorylation and might be grouped into three fundamental lessons based mostly on sequence, construction and catalytic operate.

 

The most important class of PPs is the phosphoprotein phosphatase (PPP) household comprising PP1, PP2A, PP2B, PP4, PP5, PP6 and PP7, and the protein phosphatase Mg2+- or Mn2+-dependent (PPM) household, composed primarily of PP2C. The protein Tyr phosphatase (PTP) super-family kinds the second group, and the aspartate-based protein phosphatases the third.

Mechanism
Cysteine-dependent phosphatases (CDPs) catalyse the hydrolysis of a phosphoester bond through a phospho-cysteine intermediate.Mechanism of Tyrosine dephosphorylation by a CDP.

The free cysteine nucleophile kinds a bond with the phosphorus atom of the phosphate moiety, and the P-O bond linking the phosphate group to the tyrosine is protonated, both by a suitably positioned acidic amino acid residue (Asp within the diagram under) or a water molecule. The phospho-cysteine intermediate is then hydrolysed by one other water molecule, thus regenerating the energetic web site for one more dephosphorylation response.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

Metallo-phosphatases (e.g. PP2C) co-ordinate 2 catalytically important steel ions inside their energetic web site. There may be presently some confusion of the id of those steel ions, as successive attempts to determine them yield completely different answers. There may be presently proof that these metals may very well be Magnesium, Manganese, Iron, Zinc, or any mixture thereof. It’s thought {that a} hydroxyl ion bridging the 2 steel ions takes half in nucleophilic assault on the phosphorus ion.

Physiological relevance

Phosphatases act in opposition to kinases/phosphorylases, which add phosphate teams to proteins. The addition of a phosphate group might activate or de-activate an enzyme (e.g., kinase signalling pathways[7]) or allow a protein-protein interplay to happen (e.g., SH2 domains [8]); subsequently phosphatases are integral to many sign transduction pathways. It ought to be famous that phosphate addition and removing don’t essentially correspond to enzyme activation or inhibition, and that a number of enzymes have separate phosphorylation websites for activating or inhibiting purposeful regulation.

 

CDK, for instance, might be both activated or deactivated relying on the particular amino acid residue being phosphorylated. Phosphates are necessary in sign transduction as a result of they regulate the proteins to which they’re connected. To reverse the regulatory impact, the phosphate is eliminated. This happens by itself by hydrolysis, or is mediated by protein phosphatases.

 

Protein phosphorylation performs a vital position in organic capabilities and controls almost each mobile course of, together with metabolism, gene transcription and translation, cell-cycle development, cytoskeletal rearrangement, protein-protein interactions, protein stability, cell motion, and apoptosis. These processes rely upon the extremely regulated and opposing actions of PKs and PPs, by adjustments within the phosphorylation of key proteins. Histone phosphorylation, together with methylation, ubiquitination, sumoylation and acetylation, additionally regulates entry to DNA by chromatin reorganisation.

Recombinant Candida Albicans YPI1 Protein (aa 1-124)

VAng-Lsx06074-1mgEcoli 1 mg (E. coli)
EUR 2993

Recombinant Candida Albicans YPI1 Protein (aa 1-124)

VAng-Lsx06074-500gEcoli 500 µg (E. coli)
EUR 2140

Recombinant Candida Albicans YPI1 Protein (aa 1-124)

VAng-Lsx06074-50gEcoli 50 µg (E. coli)
EUR 1480

Mammalian Cell Extraction Kit

55R-1358 500 assays
EUR 381

Mammalian Cell Extraction Kit

K2114-500 500 assays
EUR 321

Mammalian Cell Extraction Kit

K269-500
EUR 294

ProteinSeeker Mammalian Cell Lysis Solution

P9400-010 100ml
EUR 205

ProteinSeeker Mammalian Cell Lysis Solution

P9400-025 250ml
EUR 334

Anti-All Six Isotypes Of Mammalian Actin Monoclonal Antibody

M01263-1 100ul
EUR 397

Mammalian Cell Genomic DNA Isolation Kit

K967-100
EUR 381

Accuris 1 Hour Mammalian Genotyping Kit

PR1300-MG-400 1 PC
EUR 453.38
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris 1 Hour Mammalian Genotyping Kit

PR1300-MG-80 1 PC
EUR 154.32
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris 1 Hour Mammalian Genotyping Kit

PR1300-MG-S 1 PC
EUR 71.38
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

T-Cell, Immune Regulator 1 (TCIRG1) Antibody

20-abx116013
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

T-Cell, Immune Regulator 1 (TCIRG1) Antibody

20-abx174730
  • EUR 926.00
  • EUR 467.00
  • 1 mg
  • 200 ug
  • Please enquire.

T-Cell, Immune Regulator 1 (TCIRG1) Antibody

abx238558-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

T-Cell, Immune Regulator 1 (TCIRG1) Antibody

20-abx178543
  • EUR 1316.00
  • EUR 620.00
  • 1 mg
  • 200 ug
  • Please enquire.

HIF-1 Alpha Cell Based ELISA Kit

CBA-281 96 assays
EUR 612

Recombinant Trypanosoma Brucei Proteasome subunit alpha type-1 EC Protein (aa 1-266) (Mammalian cel)

VAng-Wyb8162-inquire inquire Ask for price

Human T-Cell, Immune Regulator 1 (TCIRG1) Protein

20-abx655200
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Host Cell Factor C1 Regulator 1 (HCFC1R1) Antibody

abx026360-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Host Cell Factor C1 Regulator 1 (HCFC1R1) Antibody

abx026360-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Host Cell Factor C1 Regulator 1 (HCFC1R1) Antibody

20-abx301661
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

C-type natriuretic peptide (1-22) (human, rat, swine)

B5441-1 1 mg
EUR 276

Recombinant EBOV GPDTM (mammalian)

0501-001 100ug
EUR 552

Glucokinase Regulator Cell ELISA Kit

abx595841-96tests 96 tests
EUR 637
  • Shipped within 1-2 weeks.

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

VAng-Lsx8856-1mgEcoli 1 mg (E. coli)
EUR 4555

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

VAng-Lsx8856-500gEcoli 500 µg (E. coli)
EUR 3080

Recombinant Clostridium Butyricum HTH-type transcriptional regulator malR (aa 1-335)

VAng-Lsx8856-50gEcoli 50 µg (E. coli)
EUR 2098

Bovine Collagen Type I (Skin, >97%) for cell culture

CLGN16-N-1 5 mg
EUR 529

Rac1 Activation Assay

STA-401-1 20 assays
EUR 757

Rap1 Activation Assay Kit

STA-406-1 20 assays
EUR 757

Arf1 Activation Assay

STA-407-1 20 assays
EUR 757

type II collagen fragment

A1096-1 1 mg
EUR 108

Recombinant Mycoplasma Pulmonis (Mp) protein antigens (mammalian cell produced)

MPUL15-N-10 10 ug
EUR 225

Live/Dead Cell Viability Assay Kit (for Mammalian Cells)

K502-100
EUR 457

Recombinant Rabbit AMHR2 Protein (aa 18-148) (Mammalian-Cell)

VAng-3018Lsx-100g 100 µg
EUR 4779

Recombinant Rabbit AMHR2 Protein (aa 18-148) (Mammalian-Cell)

VAng-3018Lsx-50g 50 µg
EUR 3048

Recombinant Mouse AMHR2 Protein (aa 16-147) (Mammalian-Cell)

VAng-3021Lsx-100g 100 µg
EUR 4793

Recombinant Mouse AMHR2 Protein (aa 16-147) (Mammalian-Cell)

VAng-3021Lsx-50g 50 µg
EUR 3060

Recombinant Rat AMHR2 Protein (aa 18-144) (Mammalian-Cell)

VAng-3026Lsx-100g 100 µg
EUR 4752

Recombinant Rat AMHR2 Protein (aa 18-144) (Mammalian-Cell)

VAng-3026Lsx-50g 50 µg
EUR 3048

Recombinant Human AMHR2 Protein (aa 18-149) (Mammalian-Cell)

VAng-3030Lsx-100g 100 µg
EUR 4793

Recombinant Human AMHR2 Protein (aa 18-149) (Mammalian-Cell)

VAng-3030Lsx-50g 50 µg
EUR 3060

Recombinant Dog ANGPT2 Protein (aa 19-485) (Mammalian-Cell)

VAng-3062Lsx-100g 100 µg
EUR 6443

Recombinant Dog ANGPT2 Protein (aa 19-485) (Mammalian-Cell)

VAng-3062Lsx-50g 50 µg
EUR 3995

Recombinant Rat ANGPT2 Protein (aa 19-496) (Mammalian-Cell)

VAng-3066Lsx-100g 100 µg
EUR 6443

Recombinant Rat ANGPT2 Protein (aa 19-496) (Mammalian-Cell)

VAng-3066Lsx-50g 50 µg
EUR 3995

Recombinant Pig ANGPT2 Protein (aa 19-496) (Mammalian-Cell)

VAng-3070Lsx-100g 100 µg
EUR 6443

Recombinant Pig ANGPT2 Protein (aa 19-496) (Mammalian-Cell)

VAng-3070Lsx-50g 50 µg
EUR 3995

Recombinant Mouse ANGPT2 Protein (aa 19-496) (Mammalian-Cell)

VAng-3075Lsx-100g 100 µg
EUR 6443

Recombinant Mouse ANGPT2 Protein (aa 19-496) (Mammalian-Cell)

VAng-3075Lsx-50g 50 µg
EUR 3995

Recombinant Mouse ANGPTL3 Protein (aa 17-455) (Mammalian-Cell)

VAng-3093Lsx-100g 100 µg
EUR 6292

Recombinant Mouse ANGPTL3 Protein (aa 17-455) (Mammalian-Cell)

VAng-3093Lsx-50g 50 µg
EUR 3899

Recombinant Human ANGPTL3 Protein (aa 17-460) (Mammalian-Cell)

VAng-3097Lsx-100g 100 µg
EUR 6292

Recombinant Human ANGPTL3 Protein (aa 17-460) (Mammalian-Cell)

VAng-3097Lsx-50g 50 µg
EUR 3899

Recombinant Bovine ANGPTL4 Protein (aa 24-410) (Mammalian-Cell)

VAng-3113Lsx-100g 100 µg
EUR 6113

Recombinant Bovine ANGPTL4 Protein (aa 24-410) (Mammalian-Cell)

VAng-3113Lsx-50g 50 µg
EUR 3789

Recombinant Bovine ANGPTL4 Protein (aa 24-498) (Mammalian-Cell)

VAng-3117Lsx-100g 100 µg
EUR 6429

Recombinant Bovine ANGPTL4 Protein (aa 24-498) (Mammalian-Cell)

VAng-3117Lsx-50g 50 µg
EUR 3995

Recombinant Rat ANGPTL4 Protein (aa 24-405) (Mammalian-Cell)

VAng-3121Lsx-100g 100 µg
EUR 6113

Recombinant Rat ANGPTL4 Protein (aa 24-405) (Mammalian-Cell)

VAng-3121Lsx-50g 50 µg
EUR 3789

Recombinant Pig ANGPTL4 Protein (aa 24-412) (Mammalian-Cell)

VAng-3125Lsx-100g 100 µg
EUR 6113

Recombinant Pig ANGPTL4 Protein (aa 24-412) (Mammalian-Cell)

VAng-3125Lsx-50g 50 µg
EUR 3789

Recombinant Human ANGPTL4 Protein (aa 28-403) (Mammalian-Cell)

VAng-3129Lsx-100g 100 µg
EUR 6113

Recombinant Human ANGPTL4 Protein (aa 28-403) (Mammalian-Cell)

VAng-3129Lsx-50g 50 µg
EUR 3789

Recombinant Human ANGPTL4 Protein (aa 26-406) (Mammalian-Cell)

VAng-3133Lsx-100g 100 µg
EUR 6113

Recombinant Human ANGPTL4 Protein (aa 26-406) (Mammalian-Cell)

VAng-3133Lsx-50g 50 µg
EUR 3789

Recombinant Salmonella uspA Protein (aa 2-144) (Mammalian Cell)

VAng-Wyb0670-10g 10 µg
EUR 1337

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135 96 assays
EUR 821

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Colorimetric

CBA-135-5 5 x 96 assays
EUR 3356

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140 96 assays
EUR 856

CytoSelect Cell Transformation Assay (Cell Recovery Compatible), Fluorometric

CBA-140-5 5 x 96 assays
EUR 3483

Human T-Cell, Immune Regulator 1 (TCIRG1) CLIA Kit

20-abx496051
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

abx146298-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

20-abx153240
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

20-abx004842
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

20-abx321539
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

20-abx321564
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

abx431934-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Cell Division Cycle and Apoptosis Regulator 1 (CCAR1) Antibody

20-abx212846
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) Antibody

20-abx225077
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Human T-Cell, Immune Regulator 1 (TCIRG1)ELISA Kit

201-12-2483 96 tests
EUR 440
  • This T-Cell ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

DLR-TCIRG1-Hu-48T 48T
EUR 554
  • Should the Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

DLR-TCIRG1-Hu-96T 96T
EUR 725
  • Should the Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

RD-TCIRG1-Hu-48Tests 48 Tests
EUR 563

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

RD-TCIRG1-Hu-96Tests 96 Tests
EUR 783

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

RDR-TCIRG1-Hu-48Tests 48 Tests
EUR 589

Human T-Cell, Immune Regulator 1 (TCIRG1) ELISA Kit

RDR-TCIRG1-Hu-96Tests 96 Tests
EUR 820

One of many main switches for neuronal exercise is the activation of PKs and PPs by elevated intracellular calcium. The diploma of activation of the varied isoforms of PKs and PPs is managed by their particular person sensitivities to calcium. Moreover, a variety of particular inhibitors and concentrating on companions akin to scaffolding, anchoring, and adaptor proteins additionally contribute to the management of PKs and PPs and recruit them into signalling complexes in neuronal cells. Such signalling complexes usually act to convey PKs and PPs in shut proximity with goal substrates and signalling molecules in addition to improve their selectivity by proscribing accessibility to those substrate proteins. Phosphorylation occasions, subsequently, are managed not solely by the balanced exercise of PKs and PPs but in addition by their restricted localisation.

Pleiotropic Regulator 1 (PLRG1) Antibody

Regulatory subunits and domains serve to limit particular proteins to explicit subcellular compartments and to modulate protein specificity. These regulators are essential for sustaining the coordinated motion of signalling cascades, which in neuronal cells embrace short-term (synaptic) and long-term (nuclear) signalling. These capabilities are, partially, managed by allosteric modification by secondary messengers and reversible protein phosphorylation.

 

It’s thought that round 30% of identified PPs are current in all tissues, with the remainder displaying some degree of tissue restriction. Whereas protein phosphorylation is a cell-wide regulatory mechanism, latest quantitative proteomics research have proven that phosphorylation preferentially targets nuclear proteins. Many PPs that regulate nuclear occasions, are sometimes enriched or completely current within the nucleus. In neuronal cells, PPs are current in a number of mobile compartments and play a vital position at each pre- and post-synapses, within the cytoplasm and within the nucleus the place they regulate gene expression.

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